My experience: I take the train on a daily basis because I do not have a license and can direct you to almost anywhere if I've got a map and two minutes. Here's a couple things to know about the T now, as of February 2022:
- UPDATE: As of late April 2022, masks are now optional on the MBTA.
- The Green Line, which is the main line used to get to the Hynes, is currently under construction. The Hynes and Prudential stops are not impacted. As of March 2022, trains now head out to Lechmere and to the new stop, Union Square. Anything beyond that will most likely not open by May 2022. Train end-destinations are: B and C trains terminate at Government Center, D trains terminate at North Station, and E trains at Union Square.
- They have updated the tickets and ticket machines, which may not play nice with older Charlie cards. And, as @Lamron pointed out below, your Charlie card might now be expired and you will have to get a ticket or a new card when coming into town. If you had money on it, you will have to go to Downtown Crossing to get that transferred. For getting a new card and putting your old money on it: the Downtown Crossing Charlie Card store is only open Wednesday and Friday for the general public, 12:30pm to 5pm. Tickets can still be purchased at any machine.

MBTA-ers, add on your tips about close to transit hotels, last-train out advice, and such, and those with questions: ask away!
